Anxiety & Mood
Peptides commonly researched for their effects on stress response, anxiety, attention, and mood.
These are not substitutes for psychiatric care. Anyone with a mood or anxiety disorder should work with a licensed clinician.
Selank
ExperimentalA Russian-developed heptapeptide analog of tuftsin studied as a nasal anxiolytic with minimal sedation in small clinical trials.
Semax
ExperimentalA Russian-developed ACTH(4-10) analog used intranasally and studied for cognitive performance and stroke recovery.
DSIP
ExperimentalDelta sleep-inducing peptide, a nonapeptide studied for slow-wave sleep and stress modulation since the 1970s.
Oxytocin
Moderate Human EvidenceA nine-amino-acid neuropeptide and hormone best known for its role in childbirth and lactation; FDA-approved as an injectable drug (Pitocin) for labor, and heavily studied (often via nasal spray) for social bonding, trust, anxiety, and autism with mixed, frequently non-replicating results.
Selank + Semax
ExperimentalA nootropic research blend pairing the anxiolytic peptide Selank with the cognitive/neuroprotective peptide Semax, both Russian-developed. Each has some human data (mostly Russian trials); the combination itself has not been formally studied.
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