Energy & Focus
Peptides commonly researched for cognition, attention, mitochondrial signaling, and daytime energy.
Nootropic peptides have very small human datasets. Sleep, nutrition, and exercise drive the largest effects on cognition.
NAD+
Limited Human EvidenceA central coenzyme in energy metabolism that has been studied as a supplement and IV therapy for aging, fatigue, and metabolic health.
MOTS-c
ExperimentalA mitochondrial-encoded peptide studied for its role in metabolism, exercise capacity, and mitochondrial signaling.
Selank
ExperimentalA Russian-developed heptapeptide analog of tuftsin studied as a nasal anxiolytic with minimal sedation in small clinical trials.
Semax
ExperimentalA Russian-developed ACTH(4-10) analog used intranasally and studied for cognitive performance and stroke recovery.
SS-31
Limited Human EvidenceA mitochondria-targeting tetrapeptide (elamipretide) that binds cardiolipin on the inner mitochondrial membrane; it has been tested in multiple human trials and gained FDA accelerated approval for the ultra-rare Barth syndrome in 2025, though several other primary endpoints were not met.
Selank + Semax
ExperimentalA nootropic research blend pairing the anxiolytic peptide Selank with the cognitive/neuroprotective peptide Semax, both Russian-developed. Each has some human data (mostly Russian trials); the combination itself has not been formally studied.
PeptidePedia is for educational and informational purposes only. We do not sell peptides, prescribe peptides, provide medical advice, or recommend treatment. Peptides may not be approved for human use except in specific legal prescription or clinical contexts. Always consult a licensed medical professional before making health decisions.